One Alzheimer’s Challenge: Improving the Diagnosis of High Risk Populations

Fifty Plus Racing Foundation’s purpose is to raise money to cure Alzheimer’s Disease and comfort unfunded care givers.  Alzheimer’s is in the news today.

Justin Boyd, of the The Ann Romney Center for Neurologic Diseases at the Brigham and Women’s Hospital responds:

What's exciting about this work is that it highlights an alternative strategy for preventing the process of neurodegeneration in an Alzheimer's model. More evidence is emerging that the immune system contributes to the risk of developing Alzheimer’s Disease, and this work supports this notion.

My colleagues and I are pursuing a similar approach in targeting the immune system, specifically microglia (the immune cells in the brain) which are highlighted in this work.

We must caution, however, that this approach will likely be most effective prior to Alzheimer’s Disease symptoms presenting. This still means that we must improve our ability to diagnose high risk population in order to treat this disease most effectively.

With that said, we are in the midst of a turning point for discovering and developing new treatments for Alzheimer’s Disease. Works like the one published from Prof. Carol Colton's Lab at Duke contribute to this emergence of alternative targets .

It's likely that a combination of immune modulation and inhibiting the processes elicited by amyloid will provide an effective prevention of this disease in populations at high risk.

Fifty Plus Racing Foundation is a proud sponsor of the research work being done by Justin Boyd.

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  1. […] recently published a report on a study suggesting a hopeful direction for continued research. In an earlier post we asked Dr. Justin Body in Cambridge, MA to share his perspective on what this means as we race […]